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Delineation of meiotic gene expression in male mice

Abstract:

Meiosis is a specialised cell division producing the haploid gametes required for sexual reproduction. A key function of this process is to generate genetic diversity through recombination and independent assortment of homologous chromosomes. Delineation of gene expression during this process has been challenging due to the heterogeneity of testis tissue and the lack of faithful in vitro models.

Here we jointly analyse a single-cell resolution transcriptomic dataset of ove...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Subgroup:
Human Genetics Wt Centre
Oxford college:
Linacre College
Role:
Author
ORCID:
0000-0002-2007-8978

Contributors

Role:
Supervisor
Role:
Supervisor
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Grant:
109109/Z/15/Z
Programme:
Genomic Medicine and Statistics PhD Programme
Funding agency for:
Wells, DJ
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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