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Directed differentiation of human induced pluripotent stem cells into dendritic cells displaying tolerogenic properties and resembling the CD141+ subset

Abstract:

The advent of induced pluripotent stem cells (iPSCs) has begun to revolutionize cell therapy by providing a convenient source of rare cell types not normally available from patients in sufficient numbers for therapeutic purposes. In particular, the development of protocols for the differentiation of populations of leukocytes as diverse as naïve T cells, macrophages and Natural Killer (NK) cells provides opportunities for their scale-up and quality control prior to administration. One populati...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3389/fimmu.2017.01935

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
Trinity College
Role:
Author
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Immunology Journal website
Volume:
8
Article number:
1935
Publication date:
2018-01-08
Acceptance date:
2017-12-15
DOI:
ISSN:
1664-3224
Source identifiers:
812142
Keywords:
Pubs id:
pubs:812142
UUID:
uuid:8da819e6-3498-4aa5-841b-4c399d838c78
Local pid:
pubs:812142
Deposit date:
2017-12-20

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