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Thesis

Bayesian and frequentist methods and analyses of genome-wide association studies

Abstract:

Recent technological advances and remarkable successes have led to genome-wide association studies (GWAS) becoming a tool of choice for investigating the genetic basis of common complex human diseases. These studies typically involve samples from thousands of individuals, scanning their DNA at up to a million loci along the genome to discover genetic variants that affect disease risk. Hundreds of such variants are now known for common diseases, nearly all discovered by GWAS over the last th...

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Institution:
University of Oxford
Research group:
Mathematical Genetics
Oxford college:
St Hugh's College
Department:
Mathematical,Physical & Life Sciences Division - Statistics
Role:
Author

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Role:
Supervisor
Publication date:
2009
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:8f89593e-a4ab-4df0-b297-74194be7891c
Local pid:
ora:4117

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