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Characterization and 454 pyrosequencing of major histocompatibility complex class I genes in the great tit reveal complexity in a passerine system.

Abstract:

BACKGROUND: The critical role of Major Histocompatibility Complex (Mhc) genes in disease resistance and their highly polymorphic nature make them exceptional candidates for studies investigating genetic effects on survival, mate choice and conservation. Species that harbor many Mhc loci and high allelic diversity are particularly intriguing as they are potentially under strong selection and studies of such species provide valuable information as to the mechanisms maintaining Mhc diversity. H...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2148-12-68

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More from this funder
Funding agency for:
Sheldon, B
Grant:
NE/F005725/1
Publisher:
BioMed Central Publisher's website
Journal:
BMC evolutionary biology Journal website
Volume:
12
Issue:
1
Pages:
68
Publication date:
2012-01-01
DOI:
EISSN:
1471-2148
ISSN:
1471-2148
Source identifiers:
358474
Language:
English
Keywords:
UUID:
uuid:90ab4345-0869-460d-b4d7-e63f9a2f80e3
Local pid:
pubs:358474
Deposit date:
2013-11-16

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