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Journal article

Genomic response to vitamin D supplementation in the setting of a randomized, placebo-controlled trial

Abstract:

Background

Vitamin D deficiency has been associated with multiple diseases, but the causal relevance and underlying processes are not fully understood. Elucidating the mechanisms of action of drug treatments in humans is challenging, but application of functional genomic approaches in randomized trials may afford an opportunity to systematically assess molecular responses.

Methods

In the Biochemical Efficacy and Safety Trial of Vitamin D (BEST-D), a double-blind, ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ebiom.2018.04.010

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
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Mexican Council for Science and Technology More from this funder
National Institute for Health Research More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
EBioMedicine Journal website
Volume:
31
Pages:
133-142
Publication date:
2018-04-10
Acceptance date:
2018-04-06
DOI:
EISSN:
2352-3964
Language:
English
Keywords:
Pubs id:
pubs:844666
UUID:
uuid:920534ba-ebe5-4d96-8dcc-a484660d9f7a
Local pid:
pubs:844666
Deposit date:
2018-05-03

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