Short-term ionic plasticity at GABAergic synapses.

Journal article

Fast synaptic inhibition in the brain is mediated by the pre-synaptic release of the neurotransmitter γ-Aminobutyric acid (GABA)and the post-synaptic activation of GABA-sensitive ionotropic receptors. As with excitatory synapses, it is being increasinly appreciated that a variety of plastic processes occur at inhibitory synapses, which operate over a range of timescales. Here we examine a form of activity-dependent plasticity that is somewhat unique to GABAergic transmission. This involves sh...

Expand abstract

Authors: Raimondo, J; Markram, H; Akerman, C

• Journal: Frontiers in synaptic neuroscience
• Volume: 4
• Issue: OCT
• Pages: 5
• Publication date: 2012-01-01
• DOI: 10.3389/fnsyn.2012.00005
• EISSN: 1663-3563
• Language: English
• Keywords: synaptic transmission; pH; GABA; GABAA receptors; chloride; reversal potential; short-term ionic plasticity; EGABA