Prospective multicentre randomised, double-blind, equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children: the SLEEPS (Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation) study
Children in paediatric intensive care units (PICUs) require analgesia and sedation but both undersedation and oversedation can be harmful.
Evaluation of intravenous (i.v.) clonidine as an alternative to i.v. midazolam.
Multicentre, double-blind, randomised equivalence trial.
Ten UK PICUs.
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