Journal article
Development of a polygenic risk score to improve screening for fracture risk: a genetic risk prediction study.
- Abstract:
-
BACKGROUND:
Expand abstract
Since screening programs identify only a small proportion of the population as eligible for an intervention, genomic prediction of heritable risk factors could decrease the number needing to be screened by removing individuals at low genetic risk. We therefore tested whether a polygenic risk score for heel quantitative ultrasound speed of sound (SOS)-a heritable risk factor for osteoporotic fracture-can identify low-risk individuals who can safely be excluded from a fracture ri...
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
- Publisher copy:
- 10.1371/journal.pmed.1003152
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Medicine Journal website
- Volume:
- 17
- Issue:
- 7
- Article number:
- e1003152
- Publication date:
- 2020-07-02
- Acceptance date:
- 2020-06-03
- DOI:
- EISSN:
-
1549-1676
- ISSN:
-
1549-1277
- Pmid:
-
32614825
- Pubs id:
-
1116405
- Local pid:
- pubs:1116405
Item Description
- Language:
- English
- Keywords:
- Format:
- Electronic-eCollection
Terms of use
- Copyright holder:
- Forgetta et al.
- Copyright date:
- 2020
- Rights statement:
- ©2020 Forgetta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- License:
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record