Thesis
Investigating the role of cytokines in clonal hematopoiesis
- Abstract:
-
Clonal hematopoiesis of indeterminate potential (CHIP) is a hematologic disorder in which individual hematopoietic stem cells acquire a mutation which allows them to clonally expand (Genovese et al., 2014; Jaiswal et al. 2014). CHIP is known to occur disproportionately in older adults. While CHIP itself usually remains clinically benign, it has been shown that CHIP may serve as a precursor for acute myeloid leukemia (AML), a hematologic cancer which, like clonal hematopoiesis, increases in...
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Bibliographic Details
- Type of award:
- MSc by Research
- Level of award:
- Masters
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Deposit date:
- 2021-02-22
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Terms of use
- Copyright holder:
- Fabo, T
- Copyright date:
- 2021
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