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Thesis

Investigating the role of cytokines in clonal hematopoiesis

Abstract:

Clonal hematopoiesis of indeterminate potential (CHIP) is a hematologic disorder in which individual hematopoietic stem cells acquire a mutation which allows them to clonally expand (Genovese et al., 2014; Jaiswal et al. 2014). CHIP is known to occur disproportionately in older adults. While CHIP itself usually remains clinically benign, it has been shown that CHIP may serve as a precursor for acute myeloid leukemia (AML), a hematologic cancer which, like clonal hematopoiesis, increases in...

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
Oncology
Oxford college:
Balliol College
Role:
Author

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Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
Keywords:
Deposit date:
2021-02-22

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