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Journal article

Neurocardiac regulation: from cardiac mechanisms to novel therapeutic approaches

Abstract:

Cardiac sympathetic overactivity is a well‐established contributor to the progression of neurogenic hypertension and heart failure, yet the underlying pathophysiology remains unclear. Recent studies have highlighted the importance of acutely regulated cyclic nucleotides and their effectors in the control of intracellular calcium and exocytosis. Emerging evidence now suggests that a significant component of sympathetic overactivity and enhanced transmission may arise from impaired cyclic nucle...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1113/jp276962

Authors


More by this author
Institution:
University of Oxford
Department:
Physiology Anatomy and Genetics
Role:
Author
ORCID:
0000-0003-3371-1290
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Oxford college:
Merton College
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Journal of Physiology Journal website
Volume:
598
Issue:
14
Pages:
2957-2976
Publication date:
2018-11-12
Acceptance date:
2018-10-02
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
Pmid:
30307615
Source identifiers:
927310
Language:
English
Keywords:
Pubs id:
pubs:927310
UUID:
uuid:97833bd1-deb3-432f-98dd-bb7c085f367a
Local pid:
pubs:927310
Deposit date:
2018-10-15

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