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Journal article

ATP increases Ca²⁺-activated K⁺ channel activity in isolated rat arterial smooth muscle cells

Abstract:

Large conductance Ca2+-activated K+ (KCa) channels are known to be activated by phosphorylation through cAMP- and cGMP-dependent kinase activation. In pulmonary arterial smooth muscle KCa channels are directly activated by ATP (but not by non-hydrolysable analogues) independently of the presence of cyclic nucleotides or the catalytic subunits of protein kinase. This study was designed to determine whether direct activation of KCa chann...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/0005-2736(96)00094-6

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
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Funding agency for:
Kozlowski, R
Glaxo Group Research More from this funder
Publisher:
Elsevier
Journal:
Biochimica et Biophysica Acta (BBA) - Biomembranes Journal website
Volume:
1283
Issue:
2
Pages:
192–198
Publication date:
1996-09-01
DOI:
ISSN:
0005-2736
Language:
English
Keywords:
Subjects:
UUID:
uuid:98501a93-0dd4-4668-97cc-9f2b8a06ee1b
Local pid:
ora:8101
Deposit date:
2014-02-26

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