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Journal article : Review

(ADP-ribosyl)hydrolases: structure, function, and biology

Abstract:

ADP-ribosylation is an intricate and versatile posttranslational modification involved in the regulation of a vast variety of cellular processes in all kingdoms of life. Its complexity derives from the varied range of different chemical linkages, including to several amino acid side chains as well as nucleic acids termini and bases, it can adopt. In this review, we provide an overview of the different families of (ADP-ribosyl)hydrolases. We discuss their molecular functions, physiological rol...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1101/gad.334631.119

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0001-8341-6439
More by this author
Role:
Author
ORCID:
0000-0002-5556-5549
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0002-9446-3756
Cancer Research UK More from this funder
Publisher:
Cold Spring Harbor Laboratory Press Publisher's website
Journal:
Genes and Development Journal website
Volume:
34
Issue:
5-6
Pages:
263-284
Publication date:
2020-02-06
Acceptance date:
2019-12-23
DOI:
EISSN:
1549-5477
ISSN:
0890-9369
Pmid:
32029451
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1087457
Local pid:
pubs:1087457
Deposit date:
2021-07-14

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