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Journal article

WASp‐dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

Abstract:

The immunological synapse is a highly structured and molecularly dynamic interface between communicating immune cells. Although the immunological synapse promotes T cell activation by dendritic cells, the specific organization of the immunological synapse on the dendritic cell side in response to T cell engagement is largely unknown. In this study, confocal and electron microscopy techniques were used to investigate the role of dendritic cell actin regulation ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1189/jlb.2A0215-050RR

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Oxford college:
Balliol College
Role:
Author
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Publisher:
Wiley Publisher's website
Journal:
Journal of Leukocyte Biology Journal website
Volume:
99
Issue:
5
Pages:
699-710
Publication date:
2015-11-20
Acceptance date:
2015-10-28
DOI:
EISSN:
1938-3673
ISSN:
0741-5400
Source identifiers:
619190
Keywords:
Pubs id:
pubs:619190
UUID:
uuid:988fa1f1-4dff-408f-ad8f-27e3e9487e2e
Local pid:
pubs:619190
Deposit date:
2017-06-14

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