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Journal article

Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable in Drosophila

Abstract:

Declining ejaculate performance with male age is taxonomically widespread and has broad fitness consequences. Ejaculate success requires fully functional germline (sperm) and soma (seminal fluid) components. However, some aging theories predict that resources should be preferentially diverted to the germline at the expense of the soma, suggesting differential impacts of aging on sperm and seminal fluid and trade-offs between them or, more broadly, between reproduction and lifespan. While harm...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1073/pnas.2009053117

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
ORCID:
0000-0002-3228-5480
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
ORCID:
0000-0002-9760-6185
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
ORCID:
0000-0002-2988-8061
More by this author
Role:
Author
ORCID:
0000-0002-3205-7170
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Kennedy Institute of Rheumatology Trust More from this funder
Publisher:
National Academy of Sciences Publisher's website
Journal:
Proceedings of the National Academy of Sciences Journal website
Volume:
117
Issue:
29
Pages:
17094-17103
Place of publication:
United States
Publication date:
2020-07-01
Acceptance date:
2020-05-11
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Pmid:
32611817
Language:
English
Keywords:
Pubs id:
1116109
Local pid:
pubs:1116109
Deposit date:
2020-07-09

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