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Journal article

Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia

Abstract:

The 2017 European LeukemiaNet 2017 acute myeloid leukemia (AML) risk stratification (ELN2017) is widely used for risk-stratifying patients with AML. However, its applicability in low- and middle-income countries is limited because of a lack of full cytogenetic and molecular information at diagnosis. Here, we propose an alternative for risk stratification (the Adapted Genetic Risk [AGR]), which permits cytogenetic or molecular missing data while retaining prognostic power. We first analyzed 16...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1182/bloodadvances.2019001419

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Publisher:
American Society of Hematology Publisher's website
Journal:
Blood Advances Journal website
Volume:
4
Issue:
10
Pages:
2339-2350
Publication date:
2020-05-26
Acceptance date:
2020-04-15
DOI:
EISSN:
2473-9537
ISSN:
2473-9529
Pmid:
32453839
Language:
English
Keywords:
Pubs id:
1109280
Local pid:
pubs:1109280
Deposit date:
2020-06-24

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