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Thesis

Comparative analysis of derived mutations across human populations.

Abstract:

Multiple factors, including the rate of mutation of different types, the action of natural selection, recombination and population history all influence the distribution of genetic variation within and between populations. Here, we seek to explore the relative contributions of different factors to notable aspects of the derived site frequency spectrum in different populations from the 1000 Genomes Project. Specifically, we ask whether individuals from different populations carry different ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Research group:
McVean
Oxford college:
Magdalen College
Role:
Author
More by this author
Division:
MPLS
Department:
Statistics
Role:
Author

Contributors

Division:
MPLS
Department:
Statistics
Role:
Supervisor
More from this funder
Funding agency for:
Feder, A
Publication date:
2013
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:9cd8594b-cd35-4ca7-94dd-f9dc11e8cd36
Local pid:
ora:9899
Deposit date:
2015-02-04

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