Journal article icon

Journal article

MS-rescue: a computational pipeline to increase the quality and yield of immunopeptidomics experiments

Abstract:

LC–MS/MS has become the standard platform for the characterization of immunopeptidomes, the collection of peptides naturally presented by major histocompatibility complex molecules to the cell surface. The protocols and algorithms used for immunopeptidomics data analysis are based on tools developed for traditional bottom‐up proteomics that address the identification of peptides generated by tryptic digestion. Such algorithms are generally not tailored to the specific requirements of MHC liga...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/pmic.201800357

Authors


More by this author
Role:
Author
ORCID:
0000-0002-8036-2647
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
Expand authors...
Publisher:
Wiley Publisher's website
Journal:
Proteomics Journal website
Volume:
19
Issue:
4
Article number:
1800357
Publication date:
2019-01-18
Acceptance date:
2018-12-21
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
Pmid:
30578603
Source identifiers:
954863
Language:
English
Keywords:
Pubs id:
pubs:954863
UUID:
uuid:9d8dffcb-75e6-4989-962b-bdd2326c6b4b
Local pid:
pubs:954863
Deposit date:
2019-10-28

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP