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Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

Abstract:

Spinal cord injury (SCI) induces haemodynamic instability that threatens survival1,2,3, impairs neurological recovery4,5, increases the risk of cardiovascular disease6,7, and reduces quality of life8,9. Haemodynamic instability in this context is due to the interruption of supraspinal efferent commands to sympathetic circuits located in the spinal cord10, which prevents the natural baroreflex from controlling these circuits to adjust peripheral vascular resistance. Epidural electrical stimula...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41586-020-03180-w

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Role:
Author
ORCID:
0000-0003-0551-859X
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Role:
Author
ORCID:
0000-0003-4910-8576
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Publisher:
Springer Nature Publisher's website
Journal:
Nature Journal website
Volume:
590
Issue:
7845
Pages:
308-314
Publication date:
2021-01-27
Acceptance date:
2020-12-11
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Pmid:
33505019

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