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Coevolution of the cell cycle and deferred-use cells

Abstract:

The cell cycle and cell fate decisions are interlinked in a broad range of developmental contexts in many organisms. Coordination of stem cell proliferation and differentiation is essential for normal development, organ homeostasis, and tissue repair through a direct interplay between cell cycle progression and differentiation in somatic stem cells in the skin, brain, gut, and hematopoietic system. The connection between cell cycle and cell fate decisions is present across the whole evolution...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1201/9780429445446

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author

Contributors

Role:
Editor
Role:
Editor
Publisher:
CRC Press Publisher's website
Series:
Evolutionary Cell Biology
Host title:
Deferring Development: Setting Aside Cells for Future Use in Development and Evolution
Chapter number:
3
Place of publication:
Boca Raton
Publication date:
2020-01-31
DOI:
EISBN:
9780429445446
ISBN:
9781138334281
Language:
English
Subtype:
Chapter
Pubs id:
1096471
Local pid:
pubs:1096471
Deposit date:
2020-03-25

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