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Thesis

The detection, structure and uses of extended haplotype identity in population genetic data

Abstract:

In large-scale population genomic data sets, individual chromosomes are likely to share extended regions of haplotype identity with others in the sample. Patterns of local haplotype sharing can be highly informative about many processes including historical demography, selection and recombination. However, in outbred diploid populations, the identification of extended shared haplotypes is not straightforward, particularly in the presence of low levels of genotyping error. Here, we introduc...

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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Research group:
Bioinformatics and Statistical Genetics; Professor McVean's group
Oxford college:
St Peter's College
Role:
Author

Contributors

Division:
MPLS
Department:
Statistics
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:9fabc91a-dd07-4deb-b722-f6b9110b34fb
Local pid:
ora:12411
Deposit date:
2016-03-02

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