Journal article
[Abnormal tropomyosin function in ATPase cycle in hypertrophic and dilated cardiomyopathies].
- Abstract:
-
Pathogenesis of most myopathies including inherited hypertrophic (HCM) and dilated (DCM) cardiomyopathies is based on modification of structural state of contractile proteins induced by point mutations, such as mutations in alpha-tropomyosin (TM). To understand the mechanism of abnormal function of contractile system of muscle fiber due to Glu180Gly, Asp175 or Glu40Lys, Glu54Lys mutations in alpha-TM associated with HCM or DCM, we specifically labeled alpha-TM by fluorescence probe 5-IAF afte...
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Bibliographic Details
- Journal:
- Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk
- Volume:
- 99
- Issue:
- 1
- Pages:
- 73-80
- Publication date:
- 2013-01-01
- ISSN:
-
0869-8139
- Source identifiers:
-
407854
Item Description
- Language:
- Russian
- Keywords:
- Pubs id:
-
pubs:407854
- UUID:
-
uuid:a2916465-6ed3-444d-8f75-164ff93013b2
- Local pid:
- pubs:407854
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2013
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