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Characterization of CAP5.5 and CAP5.5V, atypical calpains in Trypanosoma brucei

Abstract:

Calpains are a group of calcium-dependent cysteine proteases with roles ranging from cytoskeletal remodelling to signal transduction. In Trypanosoma brucei, the causal agent of African sleeping sickness, an unusually large number of calpain- like proteins exist, whose functions remain unknown. Recently, the procyclic form- specific cytoskeleton associated protein 5.5 (CAP5.5) and its bloodstream-specific paralogous variant, CAP5.5V were discovered to be essential for the proper morphogenes...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Gull Group
Oxford college:
St Edmund Hall
Role:
Author

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Role:
Supervisor
Publication date:
2013
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:a5e5ed80-275d-45a1-b39f-6183ac5943a5
Local pid:
ora:7136
Deposit date:
2013-08-02

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