Journal article
Smooth muscle cells in human atherosclerotic plaques express the fractalkine receptor CX3CR1 and undergo chemotaxis to the CX3C chemokine fractalkine (CX3CL1).
- Abstract:
-
BACKGROUND: Chemokines are important mediators of inflammatory cell recruitment that play a significant role in atherosclerosis. Fractalkine (CX3CL1) is an unusual membrane-bound chemokine that mediates chemotaxis through the CX3CR1 receptor. Recently, functional polymorphisms in the human CX3CR1 gene have been described that are associated with coronary artery disease. METHODS AND RESULTS: We investigated the expression of the CX3C chemokine fractalkine and its receptor CX3CR1 in human coro...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Circulation
- Volume:
- 108
- Issue:
- 20
- Pages:
- 2498-2504
- Publication date:
- 2003-11-01
- DOI:
- EISSN:
-
1524-4539
- ISSN:
-
0009-7322
- Source identifiers:
-
22711
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:22711
- UUID:
-
uuid:a6531dbd-4e01-443b-b5e4-4a6425c8320c
- Local pid:
- pubs:22711
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2003
If you are the owner of this record, you can report an update to it here: Report update to this record