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Journal article

Efferocytosis perpetuates substance accumulation inside macrophage populations

Abstract:

In both cells and animals, cannibalism can transfer harmful substances from the consumed to the consumer. Macrophages are immune cells that consume their own dead via a process called cannibalistic efferocytosis. Macrophages that contain harmful substances are found at sites of chronic inflammation, yet the role of cannibalism in this context remains unexplored. Here we take mathematical and experimental approaches to study the relationship between cannibalistic efferocytosis and substance ac...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1098/rspb.2019.0730

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Role:
Author
ORCID:
0000-0002-0457-7224
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Role:
Author
ORCID:
0000-0003-4118-1568
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Role:
Author
ORCID:
0000-0003-1824-7653
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Publisher:
Royal Society Publisher's website
Journal:
Proceedings of the Royal Society B: Biological Sciences Journal website
Volume:
286
Issue:
1904
Article number:
20190730
Publication date:
2019-06-02
Acceptance date:
2019-05-12
DOI:
EISSN:
1471-2954
ISSN:
0962-8452
Source identifiers:
1012020
Language:
English
Keywords:
Pubs id:
pubs:1012020
UUID:
uuid:aa18d727-03ba-4473-b737-c21ffd5c8808
Local pid:
pubs:1012020
Deposit date:
2019-06-12

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