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Journal article

Impaired cAMP-cGMP cross-talk during cardiac sympathetic dysautonomia.

Abstract:

Dysautonomia is a well-established contributor to the development and progression of hypertension and many other cardiovascular diseases. Sympathetic hyperactivity and vagal impairment are features of human hypertension, as well as in subjects with a familial predisposition for hypertension. This neural phenotype is also observed in the spontaneously hypertensive rat (SHR)3. Moreover, it is widely accepted that autonomic imbalance contributes to the pathogenesis of hypertension itself, where...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/19336950.2016.1259040

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Merton College
Role:
Author
Publisher:
Taylor and Francis Publisher's website
Journal:
Channels Journal website
Volume:
11
Issue:
3
Pages:
178-180
Publication date:
2016-11-01
Acceptance date:
2016-11-04
DOI:
EISSN:
1933-6969
ISSN:
1933-6950
Language:
English
Keywords:
Pubs id:
pubs:661748
UUID:
uuid:aaa7dfe5-d445-4a2d-b8bd-6b3ec5c4fa94
Local pid:
pubs:661748
Source identifiers:
661748
Deposit date:
2017-04-07

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