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Use of cardiac magnetic resonance to detect changes in metabolism in heart failure

Abstract:

The heart has a massive adenosine triphosphate (ATP) requirement, produced from the oxidation of metabolic substrates such as fat and glucose. Magnetic resonance spectroscopy offers a unique opportunity to probe this biochemistry: 31Phosphorus spectroscopy can demonstrate the production of ATP and quantify levels of the transport molecule phosphocreatine while 13Carbon spectroscopy can demonstrate the metabolic fates of glucose in real time. These techniques allow the metabolic deficits in he...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.21037/cdt.2019.12.13

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
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Publisher:
AME Publishing Company Publisher's website
Journal:
Cardiovascular Diagnosis and Therapy Journal website
Volume:
10
Issue:
3
Pages:
583-597
Publication date:
2020-06-01
Acceptance date:
2019-12-18
DOI:
EISSN:
2223-3660
ISSN:
2223-3652
Language:
English
Keywords:
Pubs id:
1114994
Local pid:
pubs:1114994
Deposit date:
2020-06-29

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