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Thesis

Cortical regulation of sleep

Abstract:

Sleep is vital but the regulation of sleep is poorly understood. Over the past decades, several subcortical regions in the mammalian brain have been identified, which promote wakefulness or sleep and constitute a ‘sleep switch’. The neurophysiology of the circadian clock, with the suprachiasmatic nucleus of the hypothalamus at its centre, has also been elucidated. However, it is still unclear how the brain tracks the accumulating sleep debt during wakefulness and adjusts the duration and i...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Vyazovskiy group / Sleep and circadian neuroscience institute (SCNI)
Oxford college:
Hertford College
Role:
Author
ORCID:
https://orcid.org/0000-0002-5535-7221

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Vyazovskiy group / Sleep and circadian neuroscience institute (SCNI)
Oxford college:
Hertford College
Role:
Supervisor
ORCID:
https://orcid.org/0000-0002-4336-6681
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Molnar group
Oxford college:
St John's College
Role:
Supervisor
ORCID:
0000-0002-6852-6004
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Sub department:
Pharmacology
Research group:
Akerman group
Oxford college:
Corpus Christi College
Role:
Supervisor
ORCID:
https://orcid.org/0000-0001-6844-4984
Institution:
Imperial College London
Role:
Examiner
ORCID:
https://orcid.org/0000-0003-4874-4212
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Sub department:
Clinical Neurosciences
Oxford college:
Merton College
Role:
Examiner
ORCID:
https://orcid.org/0000-0003-4134-6115
More from this funder
Programme:
Wellcome Trust Doctoral Training Programme in Neuroscience
Grant:
203971/Z/16/Z
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2022-07-28

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