Journal article
Heterologous versus homologous COVID-19 booster vaccination in previous recipients of two doses of CoronaVac COVID-19 vaccine in Brazil (RHH-001): a phase 4, non-inferiority, single blind, randomised study
- Abstract:
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Introduction
The inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac, Sinovac) has been widely used in a two-dose schedule. We assessed whether a third dose of the homologous or a different vaccine could boost immune responses.Methods
RHH-001 is a phase 4, participant masked, two centre, safety and immunogenicity study of Brazilian adults (18 years and older) in São Paulo or Salvador who had received two doses of CoronaVac 6 months previo... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 5.2MB)
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- Publisher copy:
- 10.1016/s0140-6736(22)00094-0
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Funding
NIHR Oxford Biomedical Research Centre
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Journal website
- Volume:
- 399
- Issue:
- 10324
- Pages:
- 521-529
- Publication date:
- 2022-01-21
- Acceptance date:
- 2022-01-05
- DOI:
- EISSN:
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1474-547X
- ISSN:
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0140-6736
- Pmid:
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35074136
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1236353
- Local pid:
- pubs:1236353
- Deposit date:
- 2022-02-03
Terms of use
- Copyright holder:
- Costa Clemens et al.
- Copyright date:
- 2022
- Rights statement:
- © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
- Licence:
- CC Attribution (CC BY)
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