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Journal article

Heterologous versus homologous COVID-19 booster vaccination in previous recipients of two doses of CoronaVac COVID-19 vaccine in Brazil (RHH-001): a phase 4, non-inferiority, single blind, randomised study

Abstract:

Introduction

The inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac, Sinovac) has been widely used in a two-dose schedule. We assessed whether a third dose of the homologous or a different vaccine could boost immune responses.

Methods

RHH-001 is a phase 4, participant masked, two centre, safety and immunogenicity study of Brazilian adults (18 years and older) in São Paulo or Salvador who had received two doses of CoronaVac 6 months previo... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s0140-6736(22)00094-0

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Contributors

Role:
Contributor
NIHR Oxford Biomedical Research Centre More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Journal website
Volume:
399
Issue:
10324
Pages:
521-529
Publication date:
2022-01-21
Acceptance date:
2022-01-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pmid:
35074136
Language:
English
Keywords:
Pubs id:
1236353
Local pid:
pubs:1236353
Deposit date:
2022-02-03

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