Journal article
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
- Abstract:
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On 24th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B.1.1.529 was announced, containing far more mutations in Spike (S) than previously reported variants. Neutralization titers of Omicron by sera from vaccinees and convalescent subjects infected with early pandemic Alpha, Beta, Gamma, or Delta are substantially reduced, or the sera failed to neutralize. Titers against Omicron are boosted by third vaccine doses and are high in both vaccinated in...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 12.1MB)
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- Publisher copy:
- 10.1016/j.cell.2021.12.046
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Authors
Funding
Bibliographic Details
- Publisher:
- Cell Press Publisher's website
- Journal:
- Cell Journal website
- Publication date:
- 2022-01-03
- Acceptance date:
- 2021-12-29
- DOI:
- EISSN:
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1097-4172
- ISSN:
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0092-8674
- Pmid:
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35081335
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1236007
- Local pid:
- pubs:1236007
- Deposit date:
- 2022-02-07
Terms of use
- Copyright holder:
- Dejnirattisai et al.
- Copyright date:
- 2022
- Rights statement:
- © 2022 The Authors. Published by Elsevier Inc.
- Licence:
- CC Attribution (CC BY)
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