Journal article
Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)
- Abstract:
-
BACKGROUND:The ability of Plasmodium falciparum parasites to develop resistance to widely used anti-malarials threatens malaria control and elimination efforts. Regular drug efficacy monitoring is essential for ensuring effective treatment policies. In low transmission settings where therapeutic efficacy studies are often not feasible, routine surveillance for molecular markers associated with anti-malarial resistance provides an alternative for the early detection of emerging resistance. Suc...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Malaria journal Journal website
- Volume:
- 18
- Article number:
- 280
- Publication date:
- 2019-08-22
- Acceptance date:
- 2019-08-13
- DOI:
- EISSN:
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1475-2875
- Pmid:
-
31438951
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1080700
- UUID:
-
uuid:b210a833-8922-4e83-8138-d791e51a82e3
- Local pid:
- pubs:1080700
- Source identifiers:
-
1080700
- Deposit date:
- 2020-01-04
Terms of use
- Copyright holder:
- Raman et al
- Copyright date:
- 2019
- Notes:
- Copyright © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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