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Thesis

Investigating the effects of oxidative stress on extracellular vesicle function and RNA cargo loading

Abstract:

Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed structures which have been suggested to play a critical role in maintaining intracellular homeostasis through the elimination of unnecessary biological material from EV-producing cells, and as a delivery system enabling intercellular communication between distant cells. Although extensive study has revealed many RNA biotypes that are associated with EVs, and has begun to elucidate the mechanisms of their packaging ...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Sub department:
Pathology Dunn School
Oxford college:
Lincoln College
Role:
Author
ORCID:
0000-0002-8034-8511

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Sub department:
Pathology Dunn School
Role:
Supervisor
Institution:
Oxford Brookes University
Role:
Supervisor
More from this funder
Programme:
Interdisciplinary Bioscience Doctoral Training Partnership
Funding agency for:
Dellar, ER
Grant:
BB/M011224/1
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2021-11-07

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