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Journal article

Heritability of malaria in Africa

Abstract:

Background: While many individual genes have been identified that confer protection against malaria, the overall impact of host genetics on malarial risk remains unknown. Methods and findings: We have used pedigree-based genetic variance component analysis to determine the relative contributions of genetic and other factors to the variability in incidence of malaria and other infectious diseases in two cohorts of children living on the coast of Kenya. In the first, we monitored the incidence ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.0020340

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Institution:
"University of Edinburgh", "University of Cambridge"
Department:
Department of Pathology
Role:
Author
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Institution:
"Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi District Hospital, Kenya"
Role:
Author
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Institution:
"Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi District Hospital, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - NDM John Radcliffe
Role:
Author
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Institution:
"Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi District Hospital, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - NDM John Radcliffe
Role:
Author
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Institution:
"Kenya Medical Research Institute/ Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi District Hospital, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Paediatrics,Department of
Role:
Author
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Funding agency for:
Mackinnon, M
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Funding agency for:
Mwangi, T
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Funding agency for:
Snow, R
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Funding agency for:
Marsh, K
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
2
Issue:
12
Article number:
e340
Publication date:
2005-12-01
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Language:
English
Keywords:
Subjects:
UUID:
uuid:b4969f00-7c8e-4b9d-82f2-2f70837af8be
Local pid:
ora:2964
Deposit date:
2009-09-15

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