Thesis
Structural modelling of transmembrane domains
- Abstract:
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Membrane proteins represent about one third of all known vertebrate proteins and over half of the current drug targets. Knowledge of their three-dimensional (3D) structure is worth millions of pounds to the pharmaceutical industry. Yet experimental structure elucidation of membrane proteins is a slow and expensive process. In the absence of experimental data, computational modelling tools can be used to close the gap between the numbers of known protein sequences and structures. However, c...
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(Dissemination version, pdf, 13.3MB)
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Authors
Contributors
+ Deane, CM
Division:
MPLS
Department:
Statistics
Role:
Supervisor
+ Shi, J
Division:
MPLS
Department:
Statistics
Role:
Supervisor
Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
Kelm, S
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:b4c9fba9-ee25-469b-8baf-b7c1d70c9d05
- Local pid:
- ora:6652
- Deposit date:
- 2013-01-14
Terms of use
- Copyright holder:
- Kelm, S
- Copyright date:
- 2012
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