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The Drosophila accessory gland as a model for prostate cancer and other pathologies

Abstract:

The human prostate is a gland of the male reproductive tract, which together with the seminal vesicles, is responsible for most seminal fluid production. It is a common site of cancer, and unlike other glands, it typically enlarges in ageing men. In flies, the male accessory glands make many major seminal fluid components. Like their human equivalents, they secrete proteins from several conserved families, including proteases, lectins and cysteine-rich secretory proteins, some of which intera...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/bs.ctdb.2016.06.001

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Phisiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Phisiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Role:
Author
John Fell Fund More from this funder
Wellcome Trust More from this funder
Medical Research Council More from this funder
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Publisher:
Elsevier Publisher's website
Volume:
121
Issue:
11
Pages:
339-375
Host title:
Current Topics in Developmental Biology
Publication date:
2016-05-01
Acceptance date:
2016-05-19
DOI:
ISSN:
1557-8933
Source identifiers:
629321
Keywords:
Pubs id:
pubs:629321
UUID:
uuid:b51bbb33-5a4a-4ed2-a5cd-7c4600a9500f
Local pid:
pubs:629321
Deposit date:
2016-06-22

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