Thesis icon

Thesis

Protein fold evolution on completed genomes: distinguishing between young and old folds

Abstract:

We review fold usage on completed genomes in order to explore protein structure evolution and assess the evolutionary relevance of current structural classification systems (SCOP and CATH). We assign folds on a set of 150 completed genomes using fold recognition methods (PSI-BLAST, SUPERFAMILY and Gene3D). The patterns of presence or absence of folds on genomes gives us insights into the relationships between folds and how we have arrived at the set of folds we see today. In particular, we de...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Research group:
Structural Bioinfomatics, Dr Charlotte Deane
Oxford college:
Jesus College
Department:
Mathematical,Physical & Life Sciences Division - Statistics
Role:
Author

Contributors

Role:
Supervisor
Publication date:
2007
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:b520fd65-e829-4ae0-bed6-47d642909889
Local pid:
ora:2509

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP