Thesis
Protein fold evolution on completed genomes: distinguishing between young and old folds
- Abstract:
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We review fold usage on completed genomes in order to explore protein structure evolution and assess the evolutionary relevance of current structural classification systems (SCOP and CATH). We assign folds on a set of 150 completed genomes using fold recognition methods (PSI-BLAST, SUPERFAMILY and Gene3D). The patterns of presence or absence of folds on genomes gives us insights into the relationships between folds and how we have arrived at the set of folds we see today. In particular, we de...
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Funding
Bibliographic Details
- Publication date:
- 2007
- Type of award:
- DPhil
- Level of award:
- Doctoral
- URN:
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uuid:b520fd65-e829-4ae0-bed6-47d642909889
- Local pid:
- ora:2509
Item Description
Terms of use
- Copyright holder:
- S Abeln & C. M. Deane
- Copyright date:
- 2007
- Notes:
- For copyright reasons some figures have been removed from the thesis file attached to this record page.
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