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Thesis

Measuring exposure to non-tuberculous mycobacteria: defining and testing novel antigens

Abstract:

The tuberculosis (TB) vaccine bacillus bacillus Calmette-Guerin (BCG) has low efficacy against pulmonary TB in the tropics, where most TB disease occurs, and where an effective TB vaccine is most needed. It is possible that new TB vaccines in development may be similarly affected, in particular those based on the current BCG vaccine. There are several hypotheses to explain this phenomenon, one of which is that exposure to related non-tuberculous mycobacteria (NTM) reduces the efficacy of t...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Jenner Vaccine Institute
Oxford college:
Lincoln College
Role:
Author

Contributors

Role:
Supervisor
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Funding agency for:
Checkley, A
Grant:
G0701309
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:b582d9c1-b6d7-41ee-a3ff-328be9e558cf
Deposit date:
2016-11-15

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