Journal article
Single-molecule, super-resolution, and functional analysis of G protein-coupled receptor behavior within the T cell immunological synapse
- Abstract:
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A central process in immunity is the activation of T cells through interaction of T cell receptors (TCRs) with agonistic peptide-major histocompatibility complexes (pMHC) on the surface of antigen presenting cells (APCs). TCR-pMHC binding triggers the formation of an extensive contact between the two cells termed the immunological synapse, which acts as a platform for integration of multiple signals determining cellular outcomes, including those from multiple co-stimulatory/inhibitory recepto...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 16.0MB)
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- Publisher copy:
- 10.3389/fcell.2020.608484
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Authors
Funding
John Fell Fund
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Cell and Developmental Biology Journal website
- Volume:
- 8
- Article number:
- 608484
- Publication date:
- 2020-01-18
- Acceptance date:
- 2020-12-21
- DOI:
- EISSN:
-
2296-634X
- Pmid:
-
33537301
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1161399
- Local pid:
- pubs:1161399
- Deposit date:
- 2021-06-30
Terms of use
- Copyright holder:
- Felce et al.
- Copyright date:
- 2020
- Rights statement:
- Copyright © 2021 Felce, Parolini, Sezgin, Céspedes, Korobchevskaya, Jones, Peng, Dong, Fritzsche, Aarts, Frater and Dustin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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