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Optimal metabolite transport in hollow fibre membrane bioreactors

Abstract:

Hollow fibre membrane bioreactors (HFMBs) provide a fast and efficient method for engineering functional tissue for use in medical treatments. Flow is utilised to overcome mass transport limitations by perfusing nutrient-rich culture medium through the fibre lumen, which can then transport along the fibre lumen or across the porous membrane wall. Cells seeded at the outer membrane wall consume the nutrient and subsequently produce waste metabolites, which are transported away through an ex...

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Publication status:
Accepted
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Oxford college:
St Anne's College
Role:
Author
ORCID:
0000-0001-5285-0523
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Name:
Engineering and Physical Sciences Research Council
Grant:
EP/S003509/1
Publisher:
Cambridge University Press
Journal:
Flow: Applications of Fluid Mechanics More from this journal
Acceptance date:
2024-06-13
EISSN:
2633-4259
Language:
English
Keywords:
Pubs id:
2008212
Local pid:
pubs:2008212
Deposit date:
2024-06-14

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