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Dopamine guides competition for cognitive control: common effects of haloperidol on working memory and response conflict

Abstract:

Several lines of evidence suggest that dopamine modulates working memory (the ability to faithfully maintain and efficiently manipulate information over time) but its specific role has not been fully defined. Nor is it clear whether any effects of dopamine are specific to memory processes or whether they reflect more general cognitive mechanisms that extend beyond the working memory domain. Here, we examine the effect of haloperidol, principally a dopamine D2 receptor antagonist, on the abili...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0003-0735-4349
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Publisher:
Elsevier Publisher's website
Journal:
Cortex Journal website
Volume:
113
Pages:
156-168
Publication date:
2018-12-21
Acceptance date:
2018-11-27
DOI:
EISSN:
1973-8102
ISSN:
0010-9452
Pmid:
30660954
Source identifiers:
965486
Language:
English
Keywords:
Pubs id:
pubs:965486
UUID:
uuid:bbcd3d79-c8e5-4c27-ac2b-1ff9068e95ba
Local pid:
pubs:965486
Deposit date:
2019-01-25

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