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Thesis

Genetic engineering of the primary/secondary metabolic interface in tobacco BY-2 cells

Abstract:

The supply of precursors from primary metabolism is often overlooked when engineering secondary metabolism for increased product yields. This is because precursor supply may be assumed to be non-limiting, and it is considered difficult to engineer primary metabolism, because control of carbon flow (flux) is generally distributed among most enzymes of the pathway.

The aim of this thesis was to increase the production of sterols, part of the isoprenoid class of secondary metabolites, ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Research group:
Biochemistry and Systems Biology Group, Department of Plant Sciences
Oxford college:
New College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK

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