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Journal article

Antibody persistence and booster responses to Split-Virion H5N1 avian Influenza vaccine in young and elderly adults

Abstract:

Avian influenza continues to circulate and remains a global health threat not least because of the associated high mortality. In this study antibody persistence, booster vaccine response and cross-clade immune response between two influenza A(H5N1) vaccines were compared. Participants aged over 18-years who had previously been immunized with a clade 1, A/Vietnam vaccine were re-immunized at 6-months with 7.5 μg of the homologous strain or at 22-months with a clade 2, alum-adjuvanted, A/Indone...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0165384

Authors


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Institution:
University of Oxford
Division:
Medical Sciences
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Paediatrics
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0002-1954-7554
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Primary Care Health Sciences
Oxford college:
All Souls College
Role:
Author
ORCID:
0000-0001-6324-6559
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
11
Issue:
11
Pages:
e0165384
Publication date:
2016-11-04
Acceptance date:
2016-10-10
DOI:
EISSN:
1932-6203
Pmid:
27814377
Source identifiers:
657318

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