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Journal article

Decreased hepcidin levels are associated with low steady-state hemoglobin in children with sickle cell disease in Tanzania

Abstract:
Background The contribution of hepcidin as a regulator of iron metabolism & erythropoiesis on the severity of anemia in sickle cell disease (SCD) remains poorly characterized, especially in Sub-Saharan African populations. The aims of the study were to determine if hepcidin is associated with severity of steady-state anemia in SCD and to investigate factors associated with hepcidin and anemia in SCD. Methods Archived samples from 199 Tanzanian children, ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ebiom.2018.07.024

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
ORCID:
0000-0001-5977-6602
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Funding agency for:
Armitage, AE
Grant:
“Hepcidin
IroninGlobalHealth”,OPP1055865
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Funding agency for:
Armitage, AE
Grant:
“Hepcidin
IroninGlobalHealth”,OPP1055865
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Funding agency for:
Drakesmith, H
Grant:
“Hepcidin
IroninGlobalHealth”,OPP1055865
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Funding agency for:
Drakesmith, H
Grant:
“Hepcidin
IroninGlobalHealth”,OPP1055865
More from this funder
Grant:
094780,080025,095009
070114
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Publisher:
Elsevier Publisher's website
Journal:
EBioMedicine Journal website
Volume:
34
Pages:
158-164
Publication date:
2018-07-25
Acceptance date:
2018-07-17
DOI:
ISSN:
2352-3964
Pmid:
30056060
Source identifiers:
892310
Language:
English
Keywords:
Pubs id:
pubs:892310
UUID:
uuid:c0c31632-3bc3-499e-b09e-ced1aed42ba2
Local pid:
pubs:892310
Deposit date:
2018-08-23

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