Journal article
MICA expression is regulated by cell adhesion and contact in a FAK/Src-dependent manner
- Abstract:
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MICA is a major ligand for the NKG2D immune receptor, which plays a key role in activating natural killer (NK) cells and cytotoxic T cells. We analyzed NKG2D ligand expression on a range of cell types and could demonstrate that MICA expression levels were closely linked to cellular growth mode. While the expression of other NKG2D ligands was largely independent of cell growth mode, MICA expression was mainly found on cells cultured as adherent cells. In addition, MICA surface expression was r...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 4.2MB)
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- Publisher copy:
- 10.3389/fimmu.2016.00687
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Authors
Funding
Secretaría Nacional de Ciencia, Tecnología e Innovación
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Immunology Journal website
- Volume:
- 7
- Issue:
- JAN
- Article number:
- 687
- Publication date:
- 2017-01-19
- Acceptance date:
- 2016-12-23
- DOI:
- ISSN:
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1664-3224
- Pmid:
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28154561
- Source identifiers:
-
679719
Item Description
Terms of use
- Copyright holder:
- Moncayo et al
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Moncayo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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