Journal article
Hyperglycaemia disrupts conducted vasodilation in the resistance vasculature of db/db mice
- Abstract:
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Vascular dysfunction in small resistance arteries is observed during chronic elevations in blood glucose. Hyperglycaemia-associated effects on endothelium-dependent vasodilation have been well characterized, but effects on conducted vasodilation in the resistance vasculature are not known. Small mesenteric arteries were isolated from healthy and diabetic db/db mice, which were used as a model of chronic hyperglycaemia. Endothelium-dependent vasodilation via the Gq/11-coupled proteinase activa...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 583.1KB)
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- Publisher copy:
- 10.1016/j.vph.2018.01.002
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Authors
Funding
+ British Heart Foundation
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Funding agency for:
Lemmey, H
Grant:
PhD Studentship
+ Qatar Foundation
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Grant:
National Priorities Research Program grant 4-9103-244
Wellcome Trust
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Vascular Pharmacology Journal website
- Volume:
- 103-105
- Pages:
- 29-35
- Publication date:
- 2018-01-12
- Acceptance date:
- 2018-01-10
- DOI:
- ISSN:
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1537-1891
- Source identifiers:
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819414
Item Description
- Keywords:
- Pubs id:
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pubs:819414
- UUID:
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uuid:c2d82259-daf8-4615-aa7d-19c459d56cae
- Local pid:
- pubs:819414
- Deposit date:
- 2018-01-14
Terms of use
- Copyright holder:
- Lemmey et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/BY/4.0/)
- Licence:
- CC Attribution (CC BY)
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