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Thesis

Dynamic functional imaging of the response of lung tumours to a potential hypoxia modifier

Abstract:

In this thesis, the kinetics of fluoromisonidazole (FMISO) uptake by lung tumours in patients with advanced stage non-small cell lung cancer (NSCLC) is analysed. The uptake data was extracted from dynamic positron emission tomography (PET) images collected in the course of a clinical trial designed to investigate the impact of Buparlisib, a potentially hypoxia-modifying drug, on perfusion and hypoxia in NSCLC patients. The trial design is a 3+3 dose escalation study exploring the effect of...

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:c4fc3c9c-2de2-4da8-91b8-e45f7a537038
Deposit date:
2016-07-08

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