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An atlas of G-protein coupled receptor expression and function in human subcutaneous adipose tissue.

Abstract:

G-protein coupled receptors (GPCRs) are involved in the regulation of adipose tissue function, but the total number of GPCRs expressed by human subcutaneous adipose tissue, as well as their function and interactions with drugs, is poorly understood. We have constructed an atlas of all GPCRs expressed by human subcutaneous adipose tissue: the 'adipose tissue GPCRome', to support the exploration of novel control nodes in metabolic and endocrine functions. This atlas describes how adipose tissue...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
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Heart Research UK More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Pharmacology and therapeutics Journal website
Volume:
146
Pages:
61–93
Publication date:
2015-02-01
DOI:
EISSN:
1879-016X
ISSN:
0163-7258
Source identifiers:
485318
Language:
English
Keywords:
UUID:
uuid:c6dccc8c-bff9-4880-800b-293156b40f45
Local pid:
pubs:485318
Deposit date:
2014-10-08

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