Journal article
A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies
- Abstract:
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Background
Mutations rapidly accumulate in the HIV-1 genome after infection. Some of those mutations are selected by host immune responses and often cause viral fitness losses. This study is to investigate whether strongly selected mutations that are not associated with immune responses result in fitness losses.
Results
Strongly selected mutations were identified by analyzing 5′-half HIV-1 genome (gag/pol) sequences from longitudinal samples of su...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
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(Version of record, pdf, 985.2KB)
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- Publisher copy:
- 10.1186/s12977-017-0371-4
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Authors
Funding
+ National Institutes of Health
More from this funder
Grant:
R01 OD011095
R01 AI028433
UM1 AI100645
U01 AI067854
U19 AI067854
R37 AI028433
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Retrovirology Journal website
- Volume:
- 14
- Article number:
- 46
- Publication date:
- 2017-10-10
- Acceptance date:
- 2017-10-03
- DOI:
- EISSN:
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1742-4690
- ISSN:
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1742-4690
- Pmid:
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29017536
- Source identifiers:
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737041
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:737041
- UUID:
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uuid:c75e0b4b-e8fd-47c4-816e-b865af4e1f72
- Local pid:
- pubs:737041
- Deposit date:
- 2018-01-25
Terms of use
- Copyright holder:
- Liu et al
- Copyright date:
- 2017
- Notes:
- © The Author(s) 2017. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
- Licence:
- CC Attribution (CC BY)
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