Journal article icon

Journal article

Genomic diversity and evolution of quasispecies in Newcastle disease virus infections

Abstract:

Newcastle disease virus (NDV) infections are well known to harbour quasispecies, due to the error-prone nature of the RNA polymerase. Quasispecies variants in the fusion cleavage site of the virus are known to significantly change its virulence. However, little is known about the genomic patterns of diversity and selection in NDV viral swarms. We analyse deep sequencing data from in vitro and in vivo NDV infections to uncover the genomic patterns of diversity and the signatures of selection w...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.3390/v12111305

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
ORCID:
0000-0002-8255-516X
Expand authors...
Biotechnology and Biological Sciences Research Council More from this funder
Publisher:
MDPI Publisher's website
Journal:
Viruses Journal website
Volume:
12
Issue:
11
Article number:
1305
Publication date:
2020-11-14
Acceptance date:
2020-11-06
DOI:
EISSN:
1999-4915
Pmid:
33202558

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP