Thesis
An analysis of the S. cerevisiae RMI1 gene
- Abstract:
-
The Saccharomyces cerevisiae Rmi1 protein is a component of the highly conserved Sgs1-Top3-Rmi1 complex, which is required for the maintenance of genome stability. The rmi1Δ deletion mutant has proven difficult to study because it exhibits very poor growth, and rapidly accumulates second site suppressor mutations. Furthermore, deletion of the putative HJ resolvase genes, MUS81-MUS81 or SLX1-SLX4 in rmi1Δ mutants causes syntheti...
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Authors
Contributors
+ Hickson, ID
Division:
MSD
Department:
Oncology
Role:
Supervisor
+ McHugh, PJ
Division:
MSD
Department:
Oncology
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2010
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:c7eb3259-ae8b-4557-9af2-7ca6b7fa5385
- Local pid:
- ora:12337
- Deposit date:
- 2015-10-29
Terms of use
- Copyright holder:
- Ashton, TM
- Copyright date:
- 2010
- Notes:
- This thesis is not currently available in ORA
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