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A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

Abstract:

Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, characterized by elevated intracranial pressure frequently manifesting with chronic headaches and visual loss. Similar to polycystic ovary syndrome (PCOS), IIH predominantly affects obese women of reproductive age. In this study, we comprehensively examined the systemic and cerebrospinal fluid (CSF) androgen metabolome in women with IIH in comparison with sex-, BMI-, and age-matched control groups with either simpl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1172/jci.insight.125348

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Role:
Author
ORCID:
0000-0002-9108-9105
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Role:
Author
ORCID:
0000-0002-5835-5643
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Publisher:
American Society for Clinical Investigation Publisher's website
Journal:
JCI insight Journal website
Volume:
4
Issue:
6
Article number:
e125348
Publication date:
2019-02-12
Acceptance date:
2019-02-05
DOI:
EISSN:
2379-3708
Pmid:
30753168
Source identifiers:
984027
Language:
English
Keywords:
Pubs id:
pubs:984027
UUID:
uuid:c998cb47-a64f-4a87-8046-e2478710f24c
Local pid:
pubs:984027
Deposit date:
2019-06-07

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